Zeuterin / Esterilsol: The New Dog Neuter, Part 3

Ark Sciences: Makers of Zeuterin™ / Esterilsol™

Zeuterin Part 1 Review:

Joe Tosini, CEO of Ark Sciences introduces the health benefits of non-surgical dog sterilization and cost benefits for the rescue community.

Zeuterin Part 2 Review:

See the recommendation of Dr. Weedon, DVM, MPH, a veterinarian with interests in dog health, curbing animal overpopulation, and global rabies control.

Please Note: Zeuterin™ wasn’t the US name at time of publication. This article was updated 1.25.2013.

Zeuterin™ / Esterilsol™ Presentation, Part 3

This series concludes with final questions posed to Dr. Weedon and Joe Tosini, by rescue representatives attending the Helen Woodward Animal Center ACES programon March 31, 2011.

An intrigued audience asked many questions, but not all could be fully addressed on-site. The following resources were made available to those in attendance. You are welcome to download the information.

The Big Recurring Question

Roaming, marking, the desire to mate and aggression – will Zeuterin™ / Esterilsol™ decrease these behavioral issues for pet owners?

This came up at the ACES presentation as well as Ark Science’s interview at Bark Out Loud Weekly (mp3). One kennel owner specifically feared the possibility of aggression when mixing surgically castrated dogs with those neutered by Zeuterin™ / Esterilsol™. According to Dr. Stephen Zawistowski (Dr. Z) of the ASPCA and Dr. James Serpell from the University of Pennsylvania, there is existing published research proving that castration changes behavior beyond a slight decrease in tendencies to roam or mark.

What Say You?

Your thoughts on the subject are welcome. Leave a line below!

Miss a post? Catch up on the complete series!


  1. When will Ark Sciences develop a chemical castration sterilant for male cats?

    • Hi Anne,

      I know that Ark Sciences would like to serve the cat community, but it means paying another 1 million dollars to the FDA for drug approval.

      At this moment, and all I can speak from is personal experience, it has been very difficult to convince veterinarians in our area to get on board using this treatment for dogs. I wonder how successful sales have been nationwide and if they are seeing enough success to move forward with cats.

      There needs to be pressure put on community vets to opt for a treatment clients want, regardless of the fact that they will make less money without having to use anesthetic, an operating room, an assisting staff, etc for this procedure. Yes, it cuts the vets’ bottom line, but I don’t understand why this option can’t be offered to rescues and shelters, leaving both traditional and chemical neuter options open to private clients. That way, it would be an add-on revenue stream, not a cut in profit.

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